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What are the signs and symptoms of uremia?

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Common signs and symptoms of uremia include nausea, vomiting, loss of appetite and weight loss, according to Norris Cotton Cancer Center. Additional symptoms include confusion, reduced awareness, agitation, seizures and coma. Uremia, or uremic syndrome, can also cause spontaneous or abnormally profuse bleeding as the result of a very minor injury.

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Other symptoms involve heart problems such as an irregular heartbeat, pericarditis and increased pressure on the heart, notes Norris Cotton Cancer Center. Patients may also experience shortness of breath from fluid buildup in the space between the lungs and the chest wall.

Uremia is a serious medical condition that stems from chronic kidney disease and acute renal failure brought on by the buildup of urea and other waste products that the kidneys cannot eliminate, explains Norris Cotton Cancer Center. As these substances build up in the body and reach high levels, they become toxic to the body.

Doctors treat uremia by addressing blood flow through the kidneys, removing nitrogen waste from the blood stream, and restoring blood volume and pressure, according to Healthgrades. Short-term treatments involve immediately stabilizing the patient and include blood transfusions, fluid therapy, hemodialysis, intravenous fluid and medication. Long-term treatment includes dialysis, diet modification and medication.

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