The signs of manic depression are episodes of mania, which includes excessive high mood or irritability, alternating with episodes of depression, which includes sadness and hopelessness, according to the Anxiety and Depression Association of America. The specific symptoms of mania and depression vary between people and from episode to episode.
To qualify as a manic episode, at least three of the primary symptoms of mania must be present for at least a week, says the Anxiety and Depression Association of America. These symptoms include increased energy, restlessness, sleeplessness, spending sprees, delusions, hallucinations, increased sex drive and aggressive behavior. Irritability requires at least four other symptoms to be diagnosed as part of a manic episode. During a manic episode, a person with manic depression will often deny that anything is wrong.
To qualify as an episode of depression, at least three of the primary symptoms must last at least two weeks, according to the Anxiety and Depression Association of America. During a depressive episode, people with manic depression can feel worthless, guilty, uninterested in activities, irritable, unable to concentrate, overly sleepy or suicidal. The symptoms of manic depression can vary in severity, and in some cases the symptoms of mania and depression can be mixed. People with manic depression also very often suffer symptoms of anxiety disorders, either constantly or periodically.