Biliary colic, an intermittent pain on the right or in the middle of the upper abdomen, is the most common symptom of gallbladder disease. Gallbladder problems also cause nausea and vomiting, pain under the shoulder blades and chronic diarrhea, according to the University of Maryland Medical Center.
The gallbladder stores bile, a substance that helps digest fats. When a person eats a snack or meal with fat in it, the gallbladder releases bile into the small intestine, as explained by WebMD. In some people, small stones form from cholesterol or pigments. If the stones are in the gallbladder, they are called gallstones, states the University of Maryland Medical Center. Another condition, acalculous gallbladder disease, occurs without the development of stones.
An attack of biliary colic is characterized by a steady pain in the upper right abdomen. This pain sometimes radiates to the upper back. In some people, nausea or vomiting accompanies the pain. If the gallbladder is inflamed due to acalculous gallbladder disease or the presence of gallstones, symptoms may include nausea and vomiting, chills, fever and severe, constant pain in the upper right abdomen. People with chronic gallbladder disease report experiencing chronic diarrhea and nausea, gas or abdominal discomfort after meals, reports the University of Maryland Medical Center.