Signs of an enlarged spleen include pain in the left, upper abdomen that could spread to the left shoulder, fatigue, easy bleeding and frequent infections, according to Mayo Clinic. People with an enlarged spleen may also feel full when they have not eaten or after eating just a small amount.
Anemia is also a sign of an enlarged spleen, explains Mayo Clinic. In some cases, patients may not have any symptoms at all.
Treatment for an enlarged spleen depends on the condition or problem causing the pain and discomfort, according to Mayo Clinic. An enlarged spleen caused by a bacterial infection is often treated with antibiotics. Physicians may recommend watchful waiting to monitor symptoms, or in severe cases, the spleen may need to be surgically removed.