What is the significance and importance of hyaline changes seen in leiomyoma?


Quick Answer

The significance of hyaline changes seen in leiomyoma is rapid growth of the fibroid tumor, and the importance is the restriction of the blood vessels to the tumor, according to Obstetrics and Gynecology International. The physical appearance of the area changes as deposits are formed on the surrounding muscle fibers.

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Full Answer

Menorrhagia, or abnormally heavy bleeding, and localized pain are indications that there is an issue with the reproductive system of a female patient. The pain is associated with the passing of large blood clots and excessive blood, leading to muscle spasms in the uterus. Patients with leiomyoma, or uterine fibroid tumors, experience these symptoms and when the tumor grows too large, degeneration begins, says the Yonsei Medical Journal. Other symptoms include increased pressure and bleeding between the normal menstrual cycle, accompanied by increased pain coinciding with the beginning and end of the cycle. The four types of degeneration that occur in patients with fibroid tumors are hyaline, red, cystic and calcific.

About 60 percent of all degeneration cases are hyaline, but red degeneration is most common in pregnant women with fibroid tumors. Hyaline fibroid tumors have an unusual appearance in the surrounding muscle fibers as a result of the deposits. Hyaline fibroid tumors are a precursor to cystic degeneration, states the Yonsei Medical Journal. Calcification degeneration occurs after menopause, according to Obstetrics and Gynecology International.

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