Common side effects of vitamin B-6 supplementation include nausea, drowsiness, headache, and tingling or mild numbness, according to eMedicineHealth. More serious side effects include tiredness, clumsiness in the hands, numbness in the feet or around the mouth, loss of coordination or balance, and decreased sensitivity to temperature and touch.
Vitamin B-6, also called pyridoxine, is a naturally occurring substance that is necessary for many of the bodyﾒs processes, notes eMedicineHealth. It works to break down carbohydrates, fats and protein found in food to make products the body needs. Doctors sometimes order supplementation with vitamin B-6 to treat nutritional deficiencies or lack of the vitamin in the body. They also recommend it for treatment of certain types of anemia, and doctors sometimes order the injectable variety of B-6 as a treatment for some seizure disorders in infants.
People considering vitamin B-6 supplementation should check with their doctors before use if they have any other medical conditions, according to eMedicineHealth. Users should also report to their doctors any food or medication allergies or report other herbal or medications used prior to supplementing with vitamin B-6. Doctors should be aware of any kidney or heart disease prior to using injectable vitamin B-6 products.