Using Zostrix cream may cause warmth, burning or stinging where it has been applied, according to WebMD. Inhaling residue from the dried cream can cause watery eyes, coughing, sneezing or throat irritation.
Patients should stop using the product and contact a doctor immediately if any serious side effects occur, states WebMD. Serious side effects may include blistering, swelling or increased, unusual pain where the cream has been applied. It is also necessary to cease product use and get immediate medical attention if serious allergic reaction symptoms are experienced, such as severe dizziness, rash, difficulty breathing, swelling or itching. Those who use Zostrix cream should avoid breathing in its dried residue. If any additional side effects are noticed, it is important to contact a pharmacist or doctor.