Dry mouth, lightheadedness, and a rapid or irregular heartbeat are the possible side effects of using Rhodiola rosea as an antidepressant, says the Memorial Sloan Kettering Cancer Center. In addition to its use as an antidepressant, rosea is also used for mental improvement and fatigue.
Rhodiola rosea is not advised for use in pregnant or breast-feeding women due to an absence of reliable information regarding its safety, according to WebMD. Using rhodiola with certain drugs could cause adverse reactions. If a person is taking antidepressants or hypertension medications in addition to medications that stimulate the central nervous system, using rhodiola is not advised due to possible increased side effects, states the Memorial Sloan Kettering Cancer Center.