Side effects of ubiquinol, also called coenzyme Q-10, include loss of appetite, stomach upset, nausea, diarrhea and vomiting, states WebMD. The vitamin-like substance can also lower blood pressure, and some individuals experience an allergic skin reaction.
Although most people tolerate ubiquinol well when taking it by mouth or applying it to the gums, it can cause mild side effects, notes WebMD. Dividing the regular dose into smaller doses to take two or three times daily can decrease the likelihood of side effects. Patients with blood pressure issues should speak with a doctor before taking ubiquinol as it can interfere with blood pressure medications. Smokers should be aware that cigarette smoking depletes the body's stores of coenzyme Q-10.
Patients should stop using ubiquinol at least two weeks before a surgery as it may interfere with blood pressure control, recommends WebMD. Ubiquinol may also decrease the effectiveness of certain chemotherapy drugs as well as the blood-clotting medication warfarin. The substance is possibly safe to use during pregnancy if taken twice daily starting at 20 weeks, but not enough is known as of 2015 to show that it is safe for use during breastfeeding. Children shouldn't use ubiquinol without a doctor's supervision. Patients should follow their doctor's dosage directions to ensure safe use.