Possible side effects of a tuberculosis skin test include pain, redness or rash at the injection site within 12 hours after administration, according to Mayo Clinic. Seek medical attention for side effects such as hives, fever or difficulty breathing. Consult a physician if blistering occurs at the injection site.
The tuberculosis, also called TB, skin test is an injection of tuberculin purified protein derivative into the top dermal layer of skin. It is used to diagnose TB infection. A positive reaction typically appears as a firm, raised bump or discrete swollen area around the administration site, explains the Mayo Clinic. After two to three days, a health care professional examines the size of the reaction in order to make a diagnosis.