Possible common side effects of Systane include mild eye irritation or burning, redness or itching in the eyes, and watery eyes, according to Drugs.com. Systane may cause vision to become blurry, and it may also cause an unpleasant taste in the mouth.
Possible side effects associated with Systane that require assistance from a doctor include vision changes, eye pain, and severe burning, stinging or eye irritation after application, states Drugs.com. Some people may have an allergic reaction to Systane. Signs of an allergic reaction include difficulty breathing and hives. An allergic reaction to Systane may also cause the face, lips, tongue or throat to swell.
Systane can cause the eyes to become more sensitive to light, notes Drugs.com. It may cause the eyelashes to mat or stick together. Systane can also cause the eyelids to swell. If the side effects of Systane persist or become concerning, it is important to speak to a health care provider for advice on preventing or reducing negative side effects.
Some side effects associated with Systane may not require medical attention, and they may subside naturally as the body gets used to the medicine, notes Drugs.com. Other unlisted side effects may be possible when using Systane. Before using Systane, it is important to tell a doctor about any prescription or over-the-counter medicines, vitamins or herbal products that may cause an interaction.