The most common side effects of the Synvisc-One shot are pain, swelling, heat, redness and fluid build-up around the knee, explains the manufacturer. However, medical studies indicate symptoms are usually mild and brief, occurring in less than 6 percent of patients.
As a precaution, patients should avoid jogging, lifting, prolonged standing and other activities that place excessive strain on the affected knee for the 48 hours following the in-office procedure, advises the manufacturer. Those with mild pain or swelling at the injection site can place an ice pack on the knee for 10 minutes or as recommended by their doctors.
Synvisc-One injections add fluid to the knee joint to relieve arthritis pain, states the manufacturer.