Studies show that sucralose is associated with blood sugar spikes as well as higher insulin levels, according to the Huffington Post. As of 2015, it is not yet known if sucralose increases the risk for Type 2 diabetes, as findings indicate that increases of insulin correspond to blood sugar elevation.
Insulin, a hormone secreted by the pancreas, assists with the absorption and storage of sugar, or glucose, in the bloodstream, according to the Huffington Post. The amount of insulin produced is proportional to how much sugar is circulating. In healthy individuals, more sugar in the bloodstream means a higher level of insulin is produced in order to manage it. Individuals with Type 2 diabetes have a higher level of resistance to insulin, causing sugar to build up and remain in the bloodstream.
Sucralose, commonly known as Splenda, has been approved by the U.S. Food and Drug Administration, or FDA, along with other artificial sweeteners such as saccharin, aspartame and stevia, according to Everyday Health. However, it is relatively newer than many artificial sweeteners and has not had ample opportunity for long-term studies on its effects. The American Diabetes Association has also approved its use for diabetics, and artificial sweeteners are generally considered better choices for those trying to manage blood sugar levels and weight.