The most prevalent side effect of Silver Sol, a commercial form of colloidal silver, or silver particles in liquid, is a condition called argyria, which turns skin a bluish-gray color, reports the National Institutes of Health. Additionally, ingesting colloidal silver can prevent the body from properly absorbing some therapeutic drugs.
Argyria, a permanent condition that impacts the skin, nails, gums and the eye membrane called the conjunctiva, may appear quickly or build up gradually, explains the U.S. Food and Drug Administration. There is no known medical treatment for argyria, and surgical treatments are not always effective. Exposure to sunlight causes the silver in the skin to increase melanin production, exacerbating the condition. Although argyria does not threaten physical health, patients who contract the condition often experience negative social and psychological ramifications.
Colloidal silver hinders the body's ability to absorb drugs such as some types of antibiotics and a thyroid deficiency drug known as thyroxine, emphasizes the National Institutes of Health. Although topical silver applied to the skin treats wounds, infections, burns and conjunctivitis, the FDA has not approved any over-the-counter or prescription drugs that involve oral ingestion of colloidal silver. Additionally, researchers have not found any nutritional benefits of silver as a dietary supplement. The Federal Trade Commission and the FDA have taken legal action against some companies for falsely representing the effectiveness of their colloidal silver products.