Common side effects of Rituxan include diarrhea, stomach pain, nausea, headache and fever, according to RXList. Flushing, night sweats, heartburn, back pain and muscle pain may also occur.
More serious side effects include ongoing cold symptoms, earache, skin sores, painful mouth ulcers and skin redness, says RXList. Patients may also experience burning during urination, less frequent urination or blood in the urine. Fainting, weak pulse, overactive reflexes and severe skin rash are also possible. Patients should contact a doctor if they experience any of these side effects even if they occur after their treatment ends.
Some patients have experienced a reaction to a Rituxan injection that may include shortness of breath, dizziness, lightheadedness, wheezing and chest pain. Patients should notify their caregiver immediately if they experience any of these side effects within 24 hours of receiving an injection.
Rituxan increases the likelihood of developing a serious brain infection whose symptoms include difficulty concentrating, difficulty walking, speech problems, confusion and vision problems, RXList states. This infection can lead to disability or death, so patients should contact their doctor immediately if they experience any of the aforementioned symptoms. Patients who experience symptoms of an allergic reaction, including hives, facial swelling or difficulty breathing, should seek emergency medical attention.