Have Any Side Effects or Risks Been Reported From Coenzyme Q10?


Quick Answer

Daily doses of 100 milligrams or more of coenzyme Q10, or CoQ10, has caused mild insomnia in some people, according to WebMD. While research has found elevated liver enzyme levels in individuals taking 300 milligrams per day for long periods of time, liver toxicity has not been reported, as of 2015.

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Full Answer

Other reported side effects include upper abdominal pain, dizziness, heartburn, fatigue and headache, states WebMD. Some individuals experience sensitivity to light, nausea, rashes and irritability. CoQ10 can decrease insulin requirements in diabetics and reduce the body’s response to certain blood thinners. Statins used to lower high cholesterol cause a decrease of CoQ10 levels and reduce the effectiveness of the supplement.

Coenzyme Q10 is an antioxidant that is naturally produced by the body and available as an over-the-counter supplement, explains Healthline. A 2013 study cited by Healthline showed that CoQ10 cuts a person’s risk of dying from heart failure in half. Because CoQ10 levels decrease in heart muscle after heart failure, patients treated with the supplement experienced fewer symptoms and saw an improved quality of life with no side effects. Additional evidence shows CoQ10 may be effective in treating high blood pressure, angina and Alzheimer’s disease. The supplement may also help decrease age-related vision problems.

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