Side effects of Novo-Methacin include upset stomach, nausea, vomiting and diarrhea, states Drugs.com. Bleeding in the stomach or intestines, serious skin reactions, decreased urination, swelling, and yellowing of the skin or eyes may also occur. Patients may also experience fever, chills, cough, unusual tiredness, and joint or muscle pain.
Treatment with Novo-Methacin increases the risk of heart attack or stroke in some patients, especially those with heart disease, according to Drugs.com. Symptoms associated with this include fast or irregular heartbeat, chest discomfort, weakness and slurred speech. If any of these symptoms occur, patients should stop taking Novo-Methacin and contact a doctor immediately.
Novo-Methacin may lead to a life-threatening allergic reaction in some patients, specifically those who are allergic to aspirin or other nonsteroidal anti-inflammatory drugs, notes Drugs.com. Patients who experience wheezing, difficulty breathing, swelling or hives are advised to seek emergency medical attention.
Novo-Methacin is a rectal suppository that contains the anti-inflammatory drug indomethacin, according to Drugs.com. Novo-Methacin treats mild to moderate pain associated with arthritis, gout and ankylosing spondylitis. It is sometimes used to treat shoulder pain caused by bursitis or tendonitis. Because multiple medications interact with Novo-Methacin, patients should inform their doctors of all medications they are taking prior to treatment.