Increased urination, reduced dopamine levels, zinc deficiencies, nausea and lowered blood pressure are side effects of nitric oxide supplementation, according to eSupplements. Nitric oxide supplements are commonly used in bodybuilding and improve circulation, muscle mass and immunity. The most common side effects are minor.
Nitric oxide supplements contain amino acids, such as arginine and citrulline, that the body uses to produce nitric oxide, explains eSupplements. To prevent some of the common side effects of nitric oxide supplementation, take the supplement as recommended by the manufacturer, take steps to increase the body's dopamine levels and take zinc supplements or eat foods rich in zinc. Individuals who suffer from hypotension should consult their doctors before using nitric oxide supplements.