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What are the side effects of methylsulfonylmethane, or MSM?

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Quick Answer

Side effects of methylsulfonylmethane include headaches, upset stomach and worsening allergy symptoms, reports MedicineNet. Allergic reactions are rare, though people who are allergic to methylsulfonylmethane may experience trouble breathing, itching and severe dizziness.

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Methylsulfonylmethane may cause bloating, nausea, insomnia and fatigue in some patients, according to WebMD. People who are allergic to MSM may experience allergic reactions such as swelling of the face, tongue and throat and rashes, reports MedicineNet. MSM has other inactive ingredients that may cause allergic reactions in patients. Therefore, people are advised to tell their pharmacist or doctor of any allergies they have before using this drug.

As a precaution, pregnant and breast-feeding women should not take this drug as it could cause harmful side effects, reports Drugs.com. Patients who are scheduled for surgery may need to stop taking products that contain MSM at least two weeks before the surgery date, according to Everyday Health. Individuals who are taking blood thinners, such as warfarin, or cancer drugs, such as etoposide, should seek medical advice before taking MSM drugs to avoid possible interactions.

People who suffer from conditions such as high blood pressure, high cholesterol, allergies and asthma should consult their pharmacist or doctor before taking drugs containing MSM, states Everyday Health. An overdose of methylsulfonylmethane may cause symptoms such as lethargy and paralysis, according to Drugs.com

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