What Are the Side Effects of MAO Inhibitors?


Quick Answer

Possible side effects of MAO inhibitors include difficulty sleeping, lightheadedness, headache and dizziness, according to Mayo Clinic. Other possible side effects include constipation, diarrhea, nausea and dry mouth. Some people may feel drowsy or have a skin reaction where the patch is placed.

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Full Answer

Less common side effects of MAO inhibitors include difficulty starting urination, aching muscles, low blood pressure and involuntary muscle jerks, states Mayo Clinic. Some people may experience difficulty reaching orgasm, diminished sexual desire, weight gain or sleep disturbances. A tingling or prickling sensation in the skin may occur after using MAO inhibitors.

Some antidepressant medications may cause problems with pregnancy, notes Mayo Clinic. However, stopping use can cause health problems, so it is important to speak to a physician if pregnancy is planned or occurs. Some foods and beverages may interact with MAO inhibitors, so it is important to speak to a physician about dietary choices. It is important to inform a doctor about any medications or supplements being taken, as MAO inhibitors can cause serious interactions.

MAO inhibitors may cause the body to produce excessive amounts of serotonin, which is a condition called serotonin syndrome, states Mayo Clinic. Signs of serotonin syndrome include increased heart rate, a lack of coordination, restlessness and confusion. Some people with serotonin syndrome may experience sweating, tremors, anxiety or agitation. It is important to seek medical attention immediately if serotonin syndrome occurs.

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