There do not seem to be side effects when people consume glucose in small doses. Intake of high levels of glucose may result in the swelling of the oral cavity, tightness in the chest and severe allergic reactions such as rashes, itching and hives, as explained by Drugs.com.
While corn syrup contains pure glucose, high fructose corn syrup (HFCS) contains high levels of fructose, as stated by the U.S. Food and Drug Administration. On the other hand, fructose is obtained by crystallizing beet juice or sugarcane. It is perhaps the most well-known food and beverage sweetener.
The liver converts the carbohydrates contained in fructose into fat, according to the Harvard Medical School. The result is a buildup of fat deposits around the liver, a condition referred to as nonalcoholic fatty liver disease.
There are no known differences in the health benefits or specific disadvantages of glucose, fructose and other traditional food sweeteners such as sucrose and honey, as reported by the U.S. Food and Drug Administration. However, a dietary guideline published in 2010 recommends all Americans to cut back the consumption of glucose, fructose and all added sugars. The side effects of glucose syrup over time are obesity, high blood sugar, high blood pressure and other related complications, according to Mayo Clinic.