Side effects of doxycycline hyclate include diarrhea, stomach upset, difficulty swallowing and nausea that can lead to vomiting, states WebMD. In rare cases, doxycycline hyclate may cause a severe intestinal condition, which may occur during or after the treatment.
Doxycycline hyclate treats certain amoeba-related infections, prevents some types of malaria and slows the growth of bacteria and anthrax progression, notes Drugs.com. A person receiving a live oral typhoid vaccine should not take doxycycline hyclate. A person who is allergic to tetracycline or who is taking isotretinoin, penicillin or acitretin also should not take doxycycline hyclate.
If a person misses a dose, he should take it immediately after remembering, and if the time nears the next dose, the patient should skip this dose and resume the normal dosing as directed, advises WebMD.