More common side effects of alprostadil include a painful erection and short-term bleeding at the injection site, according to Drugs.com. Rarer side effects include testicular pain or swelling and an erection that lasts longer than usual.Continue Reading
On rare occasions, bruising or blood clotting can occur at the site of injection due to an inappropriate injection, confirms Drugs.com. This side effect as well as bleeding and a painful erection normally go away as the patient's body adjusts to the medication, but patients can contact their doctors if side effects are bothersome or persist. Other side effects warrant an immediate consultation with a health care professional, including curving and pain during an erection, an erection that lasts four to six hours, testicular pain or swelling, and an erection that lasts for more than six hours accompanied by severe pain.
Other possible side effects of alprostadil urethral include rapid heartbeat, swelling of the leg veins and spotting from the penis, according to WebMD. Pain associated with this medication may radiate to the groin. Patients should contact a doctor immediately if they experience fainting while using alprostadil. Female partners may also experience side effects, such as vaginal burning or itching, but use of a water-based lubricant can provide relief.Learn more about Side Effects