Routine blood tests sometimes show a monoclonal gammopathy, which is an abnormal protein in the blood, according to the Mayo Clinic. When this is found, a doctor may do a monoclonal protein study to determine the type and amount of abnormal protein that is being made.
There are very rarely symptoms associated with monoclonal gammopathy, so it is usually only found during a blood test for another condition, notes the Mayo Clinic. When it is found, periodic tests including checking one's monoclonal protein levels, should be conducted to monitor the condition's progression. Checking monoclonal protein levels may also be used to help rule out other conditions associated with or caused by it. There are generally no other problems associated with monoclonal gammopathy when it is of undetermined significance.