Individuals should see a doctor about signs or symptoms of exocrine pancreatic cancer when experiencing jaundice of the skin and eyes, pain in the back or abdomen, problems with digestion, and untended weight loss, states the American Cancer Society. Symptoms appearing usually means the cancer has metastasized in the body.
People with early pancreatic cancers typically have no signs or symptoms, notes the American Cancer Society. Signs and symptoms of exocrine pancreatic cancers frequently differ from those of neuroendocrine cancers. Endocrine cancers such as gastrinomas cause signs and symptoms including fatigue, bleeding stomach ulcers, anemia and black stools. Glucagonomas produce a swollen, blistery red rash. Insulinomas produce confusion, weakness, rapid heartbeat and sweating, and carcinoid tumors cause shortness of breath and heart murmurs.