According to the American Cancer Society, men who are at the highest risk for prostate cancer should discuss screening with their doctor as early as age 40. Men in this category are those with more than one immediate family member (father, son or brother) diagnosed with prostate cancer before 65.
The ACA further explains that for African American men or men with one immediate family diagnosed before 65, this discussion should take place at age 45. Those men with only a moderate risk and who expect to live at least ten more years should have the discussion with their doctor at age 50. The patient and doctor should consider the risks, benefits, and uncertainties of testing. For men who decide to be screened, the prostate-specific antigen (PSA) blood test can be given, along with a digital rectal exam (DRE).