A persistent low-grade fever should be treated using self-care measures, such as getting enough rest, drinking fluids and taking medications like acetaminophen, ibuprofen and aspirin, according to HealthGrades. Healthgrades also notes that aspirin is not recommended for children, and ibuprofen is not recommended for infants under six months of age. A low-grade fever is classified as a body temperature between 100 to 101 degrees Fahrenheit and can occur following immunizations, be a result of teething or be a symptom of autoimmune conditions, as stated by eMedicineHealth.
A person should seek medical help if serious symptoms are paired with a low- grade fever. Serious symptoms include confusion, difficulty breathing, decreased level of consciousness, severe pain, seizures, blue coloration of the lips or nails and an increased heart rate.