Triamterene/hydrochlorothiazide is a combination medication that is safe to use in patients who have hypertension and edema, states Drugs.com. The medication is classified as a diuretic, as it forces excess water and sodium from the kidneys, according to MedlinePlus.
The hydrochlorothiazide component of the medication is an anti-hypertensive, which helps control blood pressure, but it does account for potassium and bicarbonate loss, according to Drugs.com. Triamterene is also a diuretic, and it reduces potassium loss while it increases sodium excretion in the urine.
Side effects of triamterene/hydrochlorothiazide include an irregular heartbeat, vision problems, headache and rapid weight gain, and patients exhibiting these symptoms should contact their physician immediately, states Everyday Health. Less severe side effects include a rash, nausea and dry mouth.