Is It Safe to Take Tylenol and Benadryl Together?


Quick Answer

According to WebMD, there are no drug interactions between Tylenol and Benadryl, so they can be taken at the same time. However, a personal doctor or pharmacist should always be informed, so they can add this information to the medication list.

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Full Answer

Tylenol is a brand name for acetaminophen, a type of over-the-counter pain reliever and fever reducer. Benadryl is a brand name for diphenhydramine, an over-the-counter allergy medicine. By themselves, the two medications do not cause any known drug interactions.

Although there are no interactions for them, if a patient is taking other medications in addition to these, these other medicines could result in a drug interaction where there may not have been one previously. For this reason, it is important that a patient's doctor has a correct list of medications being taken at all times.

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