If someone with a history of anaphylaxis or other acute allergic reactions is stung by a bee, WebMD recommends immediately calling 911. This is also true if someone is stung and has trouble breathing or speaking, feels that his airway is closing, is vomiting, or is unconscious.
Epinephrine should be injected as soon as possible if the victim has previously experienced anaphylaxis due to bee stings, advises WebMD. The ideal injection site is the outside part of the thigh, while the veins, backside and upper extremities should be avoided. If the person stops breathing, perform CPR. If a second epinephrine injection is needed and available, inject it 10 to 20 minutes after the first for an adult and 5 to 30 minutes after the first for a child.