Calluses can be removed by using a pumice stone to gently scrape away the tissue buildup, according to WebMD. Using cushioned insoles or pads help relieve pain as the callus heals. Medications to soften calluses can also be prescribed by health care providers.
Calluses are often treated with medicated products that work by chemically paring down the thickened skin, according to MedicineNet. These products are readily available as home remedies, and they share an active ingredient called salicylic acid. This ingredient is used in several over-the-counter treatments for wart removal. Salicylic acid remedies are found in different forms such as pads, applicators, plasters and drops. Once it is applied on the affected area, the top of the skin turns white, and the dead tissue softens enough to allow trimming or peeling away.
Some health care providers advise against the use of salicylic acid due the possibility of damaging the surrounding skin, according to WebMD. Patients using salicylic acid need to apply it only to the affected callus and refrain from using it if they have diabetes or similar conditions that involve numbness or circulatory problems. Another treatment for calluses involves having a doctor trim the affected area with a small knife. Patients are advised to never do this procedure by themselves.