According to the Laser Image Company, Restylane injections can be uncomfortable and slightly painful. A local anesthetic or topical anesthetic cream may be used when giving injections to more delicate or sensitive sites.
WebMD explains that Restylane is a filler made from hyaluronic acid, which is used to create a smoother appearance on the skin. Hyaluronic acid attracts fluid to the injection site, which seems to be the reason for its smoothing out lines and wrinkles. The effects of the filler usually last at least nine months and can last up to a year.
The skin around the application site can become red and itchy after receiving a filler injection, but according to WebMD, this is normal. However, if redness or swelling lasts over 36 hours or gets worse, WebMD suggests consulting a doctor.