The OneTouch UltraMini glucose meter is reset by using the data cable provided with the unit, notes eHow. Turn off the unit before connecting it to the computer to prevent a software malfunction.
Once the unit is connected to the computer, double click the program to launch the software. Once the software is loaded, click the Meter option and click Clear Meter Readings. This brings up the Clear Meter Readings screen, as noted by eHow. Once there, click the Clear Meter Readings option to clear the memory from the meter. Once the memory is cleared, close the program and disconnect the meter from the computer.