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What research backs up the effectiveness of Meclizine?

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Quick Answer

Various published studies demonstrate the efficacy of Meclizine, including a 2010 study on the use of the drug in treating postoperative nausea and vomiting, according to the DrugLib.com. Another study was published in 2000, which examined Meclizine's use in preventing nausea caused by emergency contraceptive pills.

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Full Answer

In 2010, 70 surgical patients were randomly assigned 50 milligrams of Meclizine or placebo orally the day before surgery, as reported by DrugLib.com. These patients were also given the same treatment the day of surgery. Those who had the placebo treatment had higher verbal scores of nausea as well as a higher incidence of nausea and vomiting. No side effects, including sedation, were reported by those who used Meclizine. Accordingly, the researchers support the use of Meclizine in preventing nausea and vomiting post surgery.

A study about Meclizine's effects on nausea and vomiting caused by emergency contraceptive pills was conducted in 2000, as DrugLib.com indicates. The study was randomized, and it attempted to determine if pretreatment with Meclizine reduces the side effects of the Yuzpe method of emergency contraception. The study found Meclizine to be an effective treatment against vomiting and nausea in this case, but the researchers who conducted it warn women to expect a sedative effect when taking Meclizine.

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