Some recommended medicines to treat incontinence include Myrbetriq and anticholinergics such as Detrol and Sanctura, according to Mayo Clinic. Myrbetriq works by relaxing the bladder and increasing the amount of urine it can hold, and anticholinergics work by blocking the chemical message sent to the brain during abnormal bladder contractions.
Imipramine is another drug that doctors sometimes prescribe for incontinence, states Mayo Clinic. It is classified as a tricyclic antidepressant that works by relaxing the muscles of the bladder while causing the smooth muscle around the neck of the bladder to contract. Additionally, a doctor may prescribe duloxetine, which is a norepinephrine reuptake inhibitor more commonly used to treat anxiety and depression but can also cause the urethral sphincter to relax.