Studies show that people who had a deficit of coenzyme Q10 while they were taking statins showed an improvement in their energy levels when they took either 100 milligrams or 300 milligrams of CoQ10 a day, says the National Center for Biotechnology Information. However, other studies showed no benefit.
Studies found that although statins are good for controlling cholesterol levels, the very mechanism by which they control those levels leads to lower levels of CoQ10, says the NCBI. The effect of statins on CoQ10 seemed especially pronounced in both older animals and older humans. The risk of CoQ10 enzyme deficiency is higher for older people whether they take statins or not, and even higher if they engage in vigorous exercise.