Doctors may need to remove granulation tissue if it becomes excessive, which can cause pain and bleeding, according to The Hysterectomy Association. When granulation tissue occurs internally, it may block the patient's airway or cause problems with medical equipment, such as tracheostomy tubes, according to the Journal of Anaesthesiology and Clinical Pharmacology.
Granulation tissue is a normal part of the healing process, notes Randy Jacobs, M.D. When a wound forms, healing requires development of a complex mesh of new tissue. This tissue appears to be pink or red, and it has a jelly-like texture rather than being smooth or solid like skin or a healed scar. This is granulation tissue.
When it grows out of control, or a new layer of skin does not form, it becomes persistent granulation tissue, according to Randy Jacobs, M.D. It is also colloquially known as proud flesh. This can occur for many reasons. Irritation of the wound is a common cause, and infection can cause it as well. Some underlying diseases, such as diabetes, interfere with normal healing and may make people more susceptible to it.
There are several treatments for hypergranulation tissue, according to Podiatry Today. Doctors often treat the area with silver nitrate, a caustic chemical that burns away the excess tissue. Surgical removal using lasers or debridement is also fairly effective.