RealDose Weight Loss Formula No. 1 is a weight loss supplement that, combined with a healthy diet and exercise, claims to burn fat, increase metabolism and curb appetite, according to customer reviews posted at RealDose.com. However, as of 2015, review websites such as Diet Pills Watchdog and Diet Spotlight have given mixed reviews, stating concerns with the lack of clinical trials and vague promises offered by the manufacturers.
While RealDose does not provide a complete ingredients list on its website, it states that the primary active ingredients in its Weight Loss Formula No. 1 are a blend of Piper betle leaf and Dolichos biflorus seed extract, green coffee bean extract, the herb Rhodiola rosea, and a thermonutrient called Bioprene. The blend is believed to increase the production of the hormone adiponectin while decreasing ghrelin, theoretically helping the body to burn more fat while reducing the appetite.
Green coffee bean extract inhibits glucose absorption and prevents carbohydrates from turning into fat cells, while R. rosea reduces production of cortisol to lower stress levels and anxiety. Bioprene is meant to make these three ingredients easier to absorb.
The lack of a complete ingredient list is a major concern for Diet Spotlight and Diet Pills Watchdog, which both state that there are no clinical trials demonstrating that the listed ingredients work as advertised and that the side effects are unknown. Furthermore, because RealDose is recommended as a supplement to a weight loss program, its efficacy alone is unknown.