Doctors recommend that one should aim for a cholesterol ratio that is below 5 to 1, but an optimum cholesterol ratio is considered to be lower than 3.5 to 1, states the University of Rochester Medical Center. A higher cholesterol ratio is linked with a higher risk factor for heart disease. To find the cholesterol ratio, other important cholesterol numbers are necessary, such as the high-density lipoprotein (HDL), or good cholesterol, and the total cholesterol number.
Cholesterol is a lipid substance found in the blood, which include low-density lipoprotein (LDL), bad cholesterol, HDL and triglycerides. A cholesterol blood panel test measures these three components and a total cholesterol number. The cholesterol ratio is found by dividing the total cholesterol number by the HDL number. The total blood cholesterol number is the addition of the HDL number, LDL numbers and 20 percent of the triglyceride count, notes the American Heart Association.