Quick treatments for cold sores include acyclovir, valacyclovir, famciclovir and penciclovir, according to Mayo Clinic. Fortunately, cold sores usually clear up without treatment in two to four weeks. These anti-viral medications are used to speed up the healing process.
Anti-viral drugs for cold sores are available as creams and pills, notes Mayo Clinic. Pills tend to work more effectively than creams. Cold sore patches that contain hydrocolloid are useful for wounds caused by cold sores. Painkillers, such as ibuprofen and paracetamol, help ease the pain. Home care measures, such as drinking plenty of water, using an antiseptic mouthwash and avoiding acidic or salty foods, help manage the condition.