What Is the Prognosis for Each Stage of Adenocarcinoma?


Quick Answer

As of 2015, the five-year observed survival rate for stage 1 adenocarcinoma is 55 percent, according to the American Cancer Society. For stage 2A, it is 49 percent, and for stage 2B, the survival rate is 35 percent. Stage 3A patients typically have a survival rate of 31 percent, and for stage 3B, the rate is 18 percent. For stage 4, the five-year survival rate of adenocarcinoma is 5 percent.

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Full Answer

In stage 1, adenocarcinoma has penetrated from the top layer of cells in the intestine to deeper layers, but it hasn't spread to local lymph nodes or to distant sites, notes the ACS. In stage 2A, the cancer has penetrated through the wall of the small intestine into the subserosa but still has not reached the local lymph nodes nor metastasized to other organs.

In stage 2B, the cancer has penetrated all the way through the intestinal wall into the serosa, but it has not invaded local lymph nodes nor distant organs, explains the ACS. In stage 3A, the adenocarcinoma has found between one and three lymph nodes but has not spread to other organs. In stage 3B, the cancer has invaded four or more local lymph nodes but has not reached distant organs. In stage 4, the cancer has metastasized to other organs, such as the liver, ovaries or lungs.

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