The prognosis for someone with L4-L5 spondylolisthesis is generally considered to be very favorable. Most people do not develop chronic pain due to this condition, notes eMedicineHealth.
Many people with L4-L5 spondylolisthesis do not exhibit any symptoms. Of those who do develop symptoms, such as back or neck pain, most tend to experience alleviation of pain within a few weeks of the onset of their symptoms, explains Spine-health.com. For patients who do experience pain, it can usually be treated and controlled by stopping the activity that may have led to vertebrae damage, taking nonsteroidal anti-inflammatory drugs such as ibuprofen or naproxen, or undergoing surgery in the most severe cases, states WebMD.
Degenerative spondylolisthesis most commonly occurs in the L4-L5 level of the lower spine, the two lowest vertebrae in the lumbar spine, although it can occur in other sections of the spine. These vertebrae, together with the attached disc, joints, nerves and soft tissues, support the upper body and allow for motion in multiple directions. Degenerative spondylolisthesis occurs when ligaments in the spine become weak and less capable of sustaining the heavy loads of the upper body. The weakness allows one vertebra to slip forward over the one below it, resulting in potential pain and discomfort, says Spine-health.com.