The five-year survival rate for someone with stage 1 Hodgkin's disease is around 90 percent, according to the American Cancer Society. This is also true for someone with stage 2 Hodgkin's disease. For stage 3 Hodgkin's disease, the survival rate drops to about 80 percent, while the survival rate for stage 4 Hodgkin's disease is about 65 percent.
This prognosis isn't true for everyone who has Hodgkin's disease, notes the American Cancer Society. Factors that affect the prognosis include whether the patient has bulky disease or B symptoms. In bulky disease, the patient has very large chest tumors or tumors that are at least 4 inches across in other parts of his body. B symptoms include the patient losing more than 10 percent of his weight over a six-month period without dieting, unexplained fevers and severe night sweats. B symptoms and bulky disease typically mean that the cancer requires more aggressive treatment.
Other factors that complicate a prognosis are being a male over the age of 45, having an elevated white blood cell count, depressed red blood cell and lymphocyte counts, and a depressed albumin level, claims the American Cancer Society. Another complication is having an elevated ESR, or erythrocyte sedimentation rate. This means a rate of more than 30 if the patient has B symptoms and more than 50 for a patient who is free of B symptoms.