Progesterone suppositories are mainly prescribed and used as part of a fertility treatment program to help women who are having hormonal problems. Since fertility treatments for women tend to decrease the progesterone levels in the body, supplementation with progesterone suppositories aims to counteract this effect.
Inadequate progesterone levels can also cause women to have irregular or no monthly periods at all. Supplementation with progesterone is also prescribed for such conditions to encourage and regulate menstruation. Progesterone suppositories are sometimes prescribed for post-menopausal women who are receiving estrogen replacement therapy. The replacement therapy treatment causes an overgrowth in the lining in the uterus and supplementation with progesterone helps prevent the overgrowth.
Progesterone suppositories contain progesterone, a female steroid hormone that is vital to the menstrual cycle, pregnancy and for the development of embryo in the womb. As part of a group of steroid hormones called progestogens, progesterone is also essential in the body's production of other endogenous steroid hormones, such as the sex hormones and corticosteroids.
Supplementation with progesterone suppositories should only be under the supervision of a medical professional. Some health conditions such as high blood pressure, kidney disease, liver disease, diabetes and even depression will have to be evaluated by a physician for proper dosage adjustment. Among the side effects that may arise from the use of progesterone suppositories include bloating, headache, swelling on both legs, mood swings and vaginal discomfort.