Not all probiotics require refrigeration, as reported by ConsumerLab. Blister packs and products containing freeze-dried microorganisms usuallydo not need to be kept inlow temperatures. However, these products should not be subjected to temperatureshigher than normal room conditions.
In humans, probiotics are beneficial microorganisms that aid in digestion. Foods and supplements containing probiotics are generally considered safe by the Food and Drug Administration, as stated by WebMD.
Heat and moisture are two factors that can inhibit the function or even kill probiotic microbes. Therefore, refrigeration is commonly practiced duringthe distribution andstorage of these products. However, advances in research have made it possible for probiotics to survive at room temperature, as claimedby the California Dairy Research Foundation. Two microorganisms that do not requirerefrigerationare Bacillus coagulans and probiotic yeast.