Lubiprostone (Amitiza) and Linaclotide (Linzess), are both prescription treatments for constipation according to Webmd.com and Medicinenet.com. The first increases water content in the stool, and the second enables people to move their bowels more frequently. Consult your doctor to find out which one is right for you.
Linzess might be the preferred treatment as it causes fewer side effects. However, you must consider your particular issue and, with your doctor, determine which one is best for you. Most doctors agree that using natural remedies, such as increasing fibre content and fluids, should be tried before prescription drugs, if at all possible.