Before taking saw palmetto supplements, people with a blood clotting or bleeding disorder, a pancreas disorder or liver disease should speak to a health care professional, according to Drugs.com. It is possible to overdose on saw palmetto, so supplements should only be taken as directed by a doctor.
Pregnant or nursing women should not take saw palmetto supplements, states Drugs.com. Because saw palmetto can increase the risk of bleeding, it should not be taken within two weeks of a surgical procedure. Saw palmetto should not be taken with other supplements that affect blood clotting.
Saw palmetto may interact with certain medications, notes Drugs.com. If an allergic reaction occurs, it is important to seek immediate medical treatment. Signs of an allergic reaction include difficulty breathing, hives and swelling of the throat, face or tongue.