Ezetimibe, a cholesterol absorption-inhibiting medication marketed as Zetia in the United States and Ezetrol in Canada, has the following "more common" side effects: fever, headache, muscle pain, runny nose and sore throat. Side effects needing immediate medical attention seem to occur less frequently, according to Drugs.com.
Ezetimibe may cause over two dozen side effects potentially serious enough to require medical attention, but the frequency of these effects has not been established, states Drugs.com. Some effects listed in this category are unusually light or dark stools; unusually dark urine; blood in stools or urine; swelling of the face, throat or other body parts; upper right abdominal pain; and yellow eyes or skin.
Drugs.com also lists more than 20 less common side effects of ezetimibe that do not necessarily need medical attention and may subside relatively quickly on their own. These include flu-like symptoms, diarrhea, dizziness, joint pain, shortness of breath, swollen glands, chest tightness and trouble swallowing. However, these symptoms should not be assumed harmless side effects of ezetimibe, especially if the body has already had time to adjust to the medication. For example, FamilyDoctor.org from the American Academy of Family Physicians lists situations in which shortness of breath requires urgent or emergency medical attention.