Potential side effects of Medrol include upset stomach, vomiting, headache, dizziness and difficulty sleeping, according to MedlinePlus. Restlessness, depression, anxiety, easy bruising and increased hair growth may also result. Women may experience irregular or absent menstrual periods while taking Medrol. Report these side effects if they are severe or unrelieved.
Medrol may also produce serious side effects that warrant immediate medical attention, including rash, swelling, vision problems, muscle weakness and black or tarry stool. A prolonged cold or infection during treatment with Medrol is another serious side effect, according to MedlinePlus. Patients are advised to speak to their doctors before suddenly stopping Medrol, due to the risk of withdrawal symptoms, including loss of appetite, upset stomach, vomiting and weight loss. Drowsiness, confusion, headache, fever, and joint and muscle pain can also result from abruptly discontinuing Medrol.
Medrol, also known as methylprednisolone, is a corticosteroid that is chemically similar to a natural hormone, according to MedlinePlus. It is prescribed to relieve inflammation and treat arthritis, severe allergies and asthma. Medrol also treats certain forms of cancer and skin, blood, kidney, eye, thyroid and intestinal problems. It is best to take Medrol with food or milk exactly as prescribed by a doctor.