There are no side effects to laser toenail removal, and success is more likely with laser treatment than oral medication, according to The Washington Post. There is a chance of recurrence of the toenail fungus infection after the laser treatment.
In comparison, one of the most common oral treatments for toenail fungus has side effects such as diarrhea, headache and rash, reports The Washington Post. Some doctors claim that although the laser treatment improves the appearance of the toenail, it is not a long-term solution because patients need repetitive procedures to ensure the fungus stays away. As of 2011, the U.S. Food and Drug Administration approves of two lasers, PinPointe and GenesisPlus, for temporary clear nail treatment.